
Drilling down to find about 75 or 100 total frames the client wanted to be changed in a half dozen layers would be a nightmare, and the project would take several hours to render. The comp would have several hundred layers. Just imagine if this project, with a total running time of just over 5 minutes was one comp. The longest render time was for Scene 1-05, a 9 second and 1 frame comp that took just over 40 minutes because it was very complicated. The render cue shows 68 renders so far with a typical render time of about 5 minutes. The master timeline shows the sections of the shot that did not need any work. The flow chart shows the 4 comps that I will need to open up in the Scene 3 section to make some changes for the client. Each master has been split up into separate comps appropriately named. The shortest Master comp from the 4 shots is 15 seconds long, the longest just over 2 minutes. Here's a current project composed of 4 different shots. Every frame came from After Effects but not one of those comps was longer than a sentence or phrase, they were all rendered and the edit was done in Premiere Pro.

A few years ago I produced 6 hour-long programs for a national client that was 100% animation. I don't think I have ever had a single AE comp longer than a minute or two in the 25 years. I know that it sounds like more work, but everything is easier to handle and you'll get finished in less time. I've been doing this for a very long time.

Occasionally I'll break up a master shot in After Effects, but I almost never render the master, I only render the sections.

The master shot or audio track is usually broken up into sections with markers in Premiere Pro for video or Audition for audio, and a separate comp is made from each section. I take a shot with a spokesman or interview, or a narration track and combine it with motion graphics. I do the kind of program you are describing all the time.
